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The principal cytochrome P450 isoenzyme included appears for being CYP2E1, with CYP1A2 and CYP3A4 as supplemental pathways. Roughly 85% of the oral dose seems during the urine inside of 24 hours of administration, most since the glucuronide conjugate, with tiny amounts of other conjugates and unchanged drug (see OVERDOSAGE) for toxicity facts.It is